Using the M50x has really been a pleasure, unless I receive a phone call. After looking around for hours, I came upon what seemed to be the easiest solution; a replacement cable with an inline mic. The NEOMUSICIA Universal Replacememt Cable with Remote and Mic has been a blessing. It works great, plugged right in to the proprietary connected on the headphones, and the other people say my voice is clean and crisp. So far I have had no issues using it with my HP Laptop and my Android Phone.
It took a great pair of headphones and made them much better! Check them out on Amazon.